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As the most abundant cells of the human brain, astrocytes play different roles in regulation and maintenance of this organ including preserving the integrity of the blood-brain barrier. They are also said to be involved in thought processing and decision making. Astrocytes are mysteriously susceptible to HIV. In this paper we review some of the outstanding research on the susceptibility of astrocytes to HIV and the mechanism by which HIV can enter astrocytes and how astrocytes’ infection with HIV determines the progress of AIDS Dementia Complex.
Document Type: Article Topic Area: Biology Submitted: 6th Jul 2017 Country: United States
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